Non-Hodgkin’s lymphoma is more common than the lymphoma — Hodgkin’s disease. The non-Hodgkin’s lymphomas are often found arising in organ sites other than lymph nodes (Example: stomach, lung, salivary glands and even such unlikely sites as brain). The non- Hodgkin’s lymphomas are derived from either B or T lymphocytes.
Non-Hodgkin’s lymphoma (NHL) is one of the most common types of cancer, and about 1 in every 50 people will develop NHL in their life time. Non-Hodgkin’s lymphoma can occur in people of any age. The number of new cases is increasing, and there are about 80% more new cases now than there were in the 1970s. Non-Hodgkin’s lymphoma can occur in both sexes, but it is a lot more common in men than in women.
Signs and Symptoms:
- Swollen lymph nodes in your neck, armpit or groin
- Abdominal pain or swelling
- Chest pain, and trouble breathing
- Fatigue
- Fever with no reason
- Night sweats
- Weight loss
The most common subtypes of non-Hodgkin’s lymphoma are:
- Diffuse large B-cell lymphoma:
A cancer of b-cells (lymphocytes) that normally exist in in the lymphatic system. The word “diffuse” defines the cell pattern. B-cells arise from the bone marrow and mature or differentiate into many cell types that tend to migrate to different areas of the body.
Figure 22: Diffuse large B-cell lymphom
- Follicular lymphoma
follicular lymphoma is a slow-growing lymphoma that arises from B-cells. It is also called an “indolent” or “low-grade” lymphoma for its slow nature. Follicular lymphoma has a slow nature both in terms of its behavior and how it looks under the microscope.
Figure 23: Follicular Lymphoma
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